Log P to free energy of transfer
Type a value in log P to get it in kJ/mol instantly.
-11.42kJ/mol
That's 6.5× as greasy as aspirin, while an ideal oral drug is 3.2× greasier. About 99.01% of it ends up in the oily layer.
What it means
Where does it go?
Log P is for the neutral molecule. For anything that ionizes, log D at a stated pH is the figure that matters in the body.
The math
How to convert log P to kJ/mol
Log P is a logarithm of the ratio: P = 10^(log P), and the share in octanol is P ÷ (1 + P) × 100 percent. The free energy of transfer is −5.708 × log P kJ/mol.
Example: 2 log P = -11.4159 kJ/mol.
Every unit
Your partition in every unit
Tables
log P to kJ/mol conversion table
| log P | kJ/mol |
|---|---|
| -3 log P | 17.1239 kJ/mol |
| -2 log P | 11.4159 kJ/mol |
| -1 log P | 5.70795 kJ/mol |
| 0 log P | 0 kJ/mol |
| 1 log P | -5.70795 kJ/mol |
| 2 log P | -11.4159 kJ/mol |
| 3 log P | -17.1239 kJ/mol |
| 4 log P | -22.8318 kJ/mol |
| 5 log P | -28.5398 kJ/mol |
| 6 log P | -34.2477 kJ/mol |
| 8 log P | -45.6636 kJ/mol |
kJ/mol to log P conversion table
| kJ/mol | log P |
|---|---|
| -3 kJ/mol | 0.525583 log P |
| -2 kJ/mol | 0.350388 log P |
| -1 kJ/mol | 0.175194 log P |
| 0 kJ/mol | 0 log P |
| 1 kJ/mol | -0.175194 log P |
| 2 kJ/mol | -0.350388 log P |
| 3 kJ/mol | -0.525583 log P |
| 4 kJ/mol | -0.700777 log P |
| 5 kJ/mol | -0.875971 log P |
| 6 kJ/mol | -1.05117 log P |
| 8 kJ/mol | -1.40155 log P |
Quick answers
Quick answers
- How many kJ/mol is 1 log P?
- 1 log P is -5.70795 kJ/mol.
- How many kJ/mol is 10 log P?
- 10 log P is -57.0795 kJ/mol.
- How many kJ/mol is 2 log P?
- 2 log P is -11.4159 kJ/mol.
The units
About these units
Log P (log P)
The base-ten logarithm of the octanol–water ratio.
Free energy of transfer (kJ/mol)
The energy of moving it from water into octanol at 25 °C.
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